WebDec 21, 2024 · Background: Systemic lupus erythematosus (SLE) is an autoimmune disease which involves multiple organs, including peripheral nervous system. Case presentation: We describe a 12-year-old boy with progressively worsening neurological symptoms as first manifestation. Legs pain, loss of balance, and lower extremity … WebMay 26, 2024 · Lupus nephritis (LN) is the most common serious complication of systemic lupus erythematosus (SLE). The pathogenesis of LN is complex, and the majority …
Immunosuppressive therapy in lupus nephritis: the Euro-Lupus
WebMar 27, 2024 · Medication Summary Corticosteroids are used in all patients with clinically significant renal disease. Immunosuppressive agents, particularly cyclophosphamide, azathioprine, and mycophenolate... WebAlthough not licensed for systemic lupus erythematosus (SLE), cyclophosphamide (CYC) has become over the last two decades the most widely prescribed cytotoxic drug for lupus nephritis (LN). A PubMed search using 'lupus nephritis and cyclophosphamide' as key words identifies not less than 454 papers on the topic. cordless refurbished chainsaws
Cyclophosphamide in lupus nephritis - PubMed
WebMar 14, 2024 · Cyclophosphamide immunotherapy is the mainstay of NPSLE treatment. We report the unique case of a patient with NPSLE who developed seizures soon after her first and second doses of low-dose cyclophosphamide. The exact pathophysiological mechanism underlying cyclophosphamide-induced seizures is not well understood. WebMar 31, 2024 · Your healthcare provider may have prescribed you the immunosuppressant drug Cytoxan (cyclophosphamide) if your lupus has gotten severe. The "gold standard" drug regimen for treating severe lupus is Cytoxan in combination with the corticosteroid methylprednisolone. 1 Hero Images / Getty Images WebThe immunosuppressives prescribed most commonly for the treatment of lupus are azathioprine (Imuran), mycophenolate (Cellcept), and cyclosporine (Neoral, … fan above cooker